The San Francisco 49ers' rushing attack presents a big test for the Seattle Seahawks and their struggling defense.

Analyzing Thursday’s San Francisco 49ers at Seattle Seahawks odds and lines, with expert NFL picks and predictions.

The race for the top spot in the NFC West heats up on Thursday night, as the San Francisco 49ers hit the road to play the ...

The NFL's Week 6 will kick off with a "Thursday Night Football" matchup between two teams coming off head-scratching losses: ...

In Week 6, wideout Jauan Jennings and the San Francisco 49ers' aerial attack will square off against the Seattle Seahawks and ...

Samuel has accumulated 19.2 fantasy points (6.4 per game) during his past three games. He has 179 yards receiving, on 12 ...

NFC West rivalry finds 49ers’ struggling red zone offense facing a Seahawks defense beaten for 71 points in two straight ...

The Seattle Seahawks could be without superstar cornerback Riq Woolen against the San Francisco 49ers on Thursday Night ...

Take advantage of a first-bet offer up to $1,500 by signing up with BetMGM bonus code SBWIRE as a new customer. Use this deal ...

Offensive coordinator Ryan Grubb says the play-action passing he wants to do suffers when he doesn’t give Walker carries.

The San Francisco 49ers square off against division rivals the Seattle Seahawks at 5:15 p.m. PDT on Thursday, Oct. 10.

Down several players on defense, the Seahawks will have their work cut out for them in stopping San Francisco quarterback ...