The EMBO Journal6h
Understanding local immunity to enable regionalized medicine
The adaptation of immune cells to their local microenvironments in our body is central to tissue homeostasis and linked to ...
The EMBO Journal6d
Author Correction: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice
The authors contacted the Journal after discovering an image re-use between Figures 3P and 4L. The authors were able to ...
The EMBO Journal9d
p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
Fibrosis and accumulation of senescent cells are common tissue changes associated with aging. Here, we show that the CDK ...
The EMBO Journal9d
Cellular senescence, p21, and the path to fibrosis
In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...
The EMBO Journal2d
Troubling bonds: lipid unsaturation promotes selenium dependency and sensitivity to ferroptosis
Reactive oxygen species (ROS), in combination with free iron (Fe 2+), can promote the damage of polyunsaturated fatty acids ...
The EMBO Journal21d
Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aneuploidy, while detrimental to untransformed ...
The EMBO Journal7d
A new class of capsid-targeting inhibitors that specifically block HIV-1 nuclear import
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. HIV-1 capsids cross nuclear pore complexes ...
The EMBO Journal3d
Ageing-associated long non-coding RNA extends lifespan and reduces translation in non-dividing cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The long-non-coding RNA aal1 ...
The EMBO Journal6d
Bacterial RNA sensing by TLR8 requires RNase 6 processing and is inhibited by RNA 2’O-methylation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TLR8 senses single-stranded RNA (ssRNA) ...
The EMBO Journal5d
A human progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Barrier-to-autointegration factor (BAF) is an ...
The EMBO Journal6d
A regulatory module mediating temperature control of cell-cell communication facilitates tree bud dormancy release
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The control of cell–cell communication via ...